Within CHEERIO we provide following services: - Gene query. Assess the regulation of a gene of interest during hypertrophic cardiac growth by examining its expression patterns in multiple in vitro and in vivo hypertrophy datasets. - Contrast query. Compare data of interest to analyze consistent gene signatures across selected hypertrophy datasets to identify conserved regulation of gene expression. -Functional Analysis.. Explore the estimated activities of a transcription factors and pathways of interest in different hypertrophy datasets. - Enrichment analysis.. Explore whether a user-uploaded gene set of interest is enriched in a selected hypertrophy dataset. -Download Center. Simple one-click download of the analyzed dataset of interest.
designed to interactively explore the results of link to manuscript.
Jan Lanzer () at the Saezlab, Institute for Computational Biomedicine, University of Heidelberg and Christoph Hofmann () at the Völkerslab, Department of Internal Medicine III Cardiology, Angiology and Pneumology, Heidelberg University Hospital.
developed using Shiny.
Source code is available on GitHub.
Please use GitHub’s issue system to address questions, bugs or feedback.
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